Omeprazole for acute upper gastrointestinal bleeding.
نویسندگان
چکیده
منابع مشابه
Omeprazole versus placebo for acute upper gastrointestinal bleeding: randomised double blind controlled trial.
OBJECTIVE To investigate the possible therapeutic role of omeprazole, a powerful proton pump inhibitor, in unselected patients presenting with upper gastrointestinal bleeding. DESIGN Double blind placebo controlled parallel group study. Active treatment was omeprazole 80 mg intravenously immediately, then three doses of 40 mg intravenously at eight hourly intervals, then 40 mg orally at 12 ho...
متن کاملTransfusion strategy for acute upper gastrointestinal bleeding.
Clinical question Does a hemoglobin transfusion threshold of 70 g/L yield better patient outcomes than a threshold of 90 g/L in patients with acute upper gastrointestinal bleeding? Article chosen Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368(1):11-21. Study objectives The authors of this study measured mortality, ...
متن کاملTransfusion strategies for acute upper gastrointestinal bleeding.
BACKGROUND The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. METHODS We enrolled 921 patients with severe acute upper gastrointestinal bleeding and randomly assigned 461 of them to a restrictive strategy ...
متن کاملThe management of acute upper gastrointestinal bleeding.
Acute upper gastrointestinal (GI) bleeding is one of the most common medical emergencies and most cases require urgent medical assessment. Half of all cases are due to peptic ulcer and this article focuses on non-variceal bleeding. The priority, following emergency hospital admission, is to support the circulation of the shocked patient rather than to identify the source of bleeding. After resu...
متن کاملMultidisciplinary management strategies for acute non-variceal upper gastrointestinal bleeding.
BACKGROUND The modern management of acute non-variceal upper gastrointestinal bleeding is centred on endoscopy, with recourse to interventional radiology and surgery in refractory cases. The appropriate use of intervention to optimize outcomes is reviewed. METHODS A literature search was undertaken of PubMed and the Cochrane Central Register of Controlled Trials between January 1990 and April...
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ژورنال
عنوان ژورنال: BMJ
سال: 1992
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.304.6823.383-a